Modulation of N-glycosylation by mesalamine facilitates membranous E-cadherin expression in colon epithelial cells()

Genome wide association studies have implicated intestinal barrier function genes in the pathogenesis of ulcerative colitis. One of such loci CDH1, encoding E-cadherin, a transmembrane glycoprotein with known tumor suppressor functions, is also linked to the susceptibility to colorectal cancer. Loss...

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Detalles Bibliográficos
Autores principales: Khare, Vineeta, Lang, Michaela, Dammann, Kyle, Campregher, Christoph, Lyakhovich, Alex, Gasche, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Gastrointestinal Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905164/
https://www.ncbi.nlm.nih.gov/pubmed/24184502
http://dx.doi.org/10.1016/j.bcp.2013.10.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905164/
https://www.ncbi.nlm.nih.gov/pubmed/24184502
http://dx.doi.org/10.1016/j.bcp.2013.10.021

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