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Modulation of N-glycosylation by mesalamine facilitates membranous E-cadherin expression in colon epithelial cells()
Genome wide association studies have implicated intestinal barrier function genes in the pathogenesis of ulcerative colitis. One of such loci CDH1, encoding E-cadherin, a transmembrane glycoprotein with known tumor suppressor functions, is also linked to the susceptibility to colorectal cancer. Loss...
Autores principales: | Khare, Vineeta, Lang, Michaela, Dammann, Kyle, Campregher, Christoph, Lyakhovich, Alex, Gasche, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905164/ https://www.ncbi.nlm.nih.gov/pubmed/24184502 http://dx.doi.org/10.1016/j.bcp.2013.10.021 |
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