Flexible Gates Generate Occluded Intermediates in the Transport Cycle of LacY()

The major facilitator superfamily (MFS) transporter lactose permease (LacY) alternates between cytoplasmic and periplasmic open conformations to co-transport a sugar molecule together with a proton across the plasma membrane. Indirect experimental evidence suggested the existence of an occluded tran...

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Detalles Bibliográficos
Autores principales: Stelzl, Lukas S., Fowler, Philip W., Sansom, Mark S.P., Beckstein, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905165/
https://www.ncbi.nlm.nih.gov/pubmed/24513108
http://dx.doi.org/10.1016/j.jmb.2013.10.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905165/
https://www.ncbi.nlm.nih.gov/pubmed/24513108
http://dx.doi.org/10.1016/j.jmb.2013.10.024

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