Cargando…
Flexible Gates Generate Occluded Intermediates in the Transport Cycle of LacY()
The major facilitator superfamily (MFS) transporter lactose permease (LacY) alternates between cytoplasmic and periplasmic open conformations to co-transport a sugar molecule together with a proton across the plasma membrane. Indirect experimental evidence suggested the existence of an occluded tran...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905165/ https://www.ncbi.nlm.nih.gov/pubmed/24513108 http://dx.doi.org/10.1016/j.jmb.2013.10.024 |