Treatment with d-penicillamine or zinc sulphate affects copper metabolism and improves but not normalizes antioxidant capacity parameters in Wilson disease

Copper accumulation in tissues due to a biallelic pathogenic mutation of the gene: ATP7B results in a clinical phenotype known as Wilson disease (WD). Aberrations in copper homeostasis can create favourable conditions for superoxide-yielding redox cycling and oxidative tissue damage. Drugs used in W...

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Detalles Bibliográficos
Autores principales: Grażyna, Gromadzka, Agata, Karpińska, Adam, Przybyłkowski, Tomasz, Litwin, Agata, Wierzchowska-Ciok, Karolina, Dzieżyc, Grzegorz, Chabik, Anna, Członkowska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905172/
https://www.ncbi.nlm.nih.gov/pubmed/24368744
http://dx.doi.org/10.1007/s10534-013-9694-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905172/
https://www.ncbi.nlm.nih.gov/pubmed/24368744
http://dx.doi.org/10.1007/s10534-013-9694-3

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