Synthesis and pharmacological evaluation of pyrazolopyrimidopyrimidine derivatives: anti-inflammatory agents with gastroprotective effect in rats

We report the synthesis of new anti-inflammatory 1,7-dihydropyrazolo[3′,4′:4,5]pyrimido[1,6-a]pyrimidine 5 from aminocyanopyrazole. All compounds were characterized by physical, chemical and spectral studies. Preliminary pharmacological evaluation of the resulting products showed that compounds 5a,...

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Detalles Bibliográficos
Autores principales: Karoui, Amine, Allouche, Fatma, Deghrigue, Monia, Agrebi, Asma, Bouraoui, Abderrahman, Chabchoub, Fakher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905175/
https://www.ncbi.nlm.nih.gov/pubmed/24489456
http://dx.doi.org/10.1007/s00044-013-0742-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905175/
https://www.ncbi.nlm.nih.gov/pubmed/24489456
http://dx.doi.org/10.1007/s00044-013-0742-x

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