Cargando…
Exploring the potential benefits of stratified false discovery rates for region-based testing of association with rare genetic variation
When analyzing the data that arises from exome or whole-genome sequencing studies, window-based tests, (i.e., tests that jointly analyze all genetic data in a small genomic region), are very popular. However, power is known to be quite low for finding associations with phenotypes using these tests,...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905218/ https://www.ncbi.nlm.nih.gov/pubmed/24523729 http://dx.doi.org/10.3389/fgene.2014.00011 |