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Exploring the potential benefits of stratified false discovery rates for region-based testing of association with rare genetic variation
When analyzing the data that arises from exome or whole-genome sequencing studies, window-based tests, (i.e., tests that jointly analyze all genetic data in a small genomic region), are very popular. However, power is known to be quite low for finding associations with phenotypes using these tests,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905218/ https://www.ncbi.nlm.nih.gov/pubmed/24523729 http://dx.doi.org/10.3389/fgene.2014.00011 |