Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by symptoms related to altered social interactions/communication and restricted and repetitive behaviors. In addition to genetic risk, epigenetic mechanisms (which include DNA methylation/demethylation) are thought to be i...

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Detalles Bibliográficos
Autores principales: Zhubi, A, Chen, Y, Dong, E, Cook, E H, Guidotti, A, Grayson, D R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905233/
https://www.ncbi.nlm.nih.gov/pubmed/24448211
http://dx.doi.org/10.1038/tp.2013.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905233/
https://www.ncbi.nlm.nih.gov/pubmed/24448211
http://dx.doi.org/10.1038/tp.2013.123

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