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Network reconstruction of platelet metabolism identifies metabolic signature for aspirin resistance

Recently there has not been a systematic, objective assessment of the metabolic capabilities of the human platelet. A manually curated, functionally tested, and validated biochemical reaction network of platelet metabolism, iAT-PLT-636, was reconstructed using 33 proteomic datasets and 354 literatur...

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Detalles Bibliográficos
Autores principales: Thomas, Alex, Rahmanian, Sorena, Bordbar, Aarash, Palsson, Bernhard Ø., Jamshidi, Neema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905279/
https://www.ncbi.nlm.nih.gov/pubmed/24473230
http://dx.doi.org/10.1038/srep03925