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Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways

BACKGROUND: Mechanical stimulation is necessary for regulating correct formation of the skeleton. Here we test the hypothesis that mechanical stimulation of the embryonic skeletal system impacts expression levels of genes implicated in developmentally important signalling pathways in a genome wide a...

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Detalles Bibliográficos
Autores principales: Rolfe, Rebecca A, Nowlan, Niamh C, Kenny, Elaine M, Cormican, Paul, Morris, Derek W, Prendergast, Patrick J, Kelly, Daniel, Murphy, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905281/
https://www.ncbi.nlm.nih.gov/pubmed/24443808
http://dx.doi.org/10.1186/1471-2164-15-48