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Engineering the Caenorhabditis elegans Genome Using Cas9-Triggered Homologous Recombination

Study of the nematode Caenorhabditis elegans has provided important insights in a wide range of fields in biology. The ability to precisely modify genomes is critical to fully realize the utility of model organisms. Here, we report a method to edit the C. elegans genome using the Clustered Regularly...

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Detalles Bibliográficos
Autores principales: Dickinson, Daniel J., Ward, Jordan D., Reiner, David J., Goldstein, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905680/
https://www.ncbi.nlm.nih.gov/pubmed/23995389
http://dx.doi.org/10.1038/nmeth.2641