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Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase

One of the hallmarks of cancers is the silencing of tumour suppressor genes and pathways. The Hippo tumour suppressor pathway is inactivated in many types of cancers, leading to tumour progression and metastasis. However, the mechanisms of pathway inactivation in tumours remain unclear. Here we demo...

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Detalles Bibliográficos
Autores principales: Serrano, Isabel, McDonald, Paul C., Lock, Frances, Muller, William J., Dedhar, Shoukat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905719/
https://www.ncbi.nlm.nih.gov/pubmed/24356468
http://dx.doi.org/10.1038/ncomms3976