Cargando…
Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase
One of the hallmarks of cancers is the silencing of tumour suppressor genes and pathways. The Hippo tumour suppressor pathway is inactivated in many types of cancers, leading to tumour progression and metastasis. However, the mechanisms of pathway inactivation in tumours remain unclear. Here we demo...
Autores principales: | Serrano, Isabel, McDonald, Paul C., Lock, Frances, Muller, William J., Dedhar, Shoukat |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905719/ https://www.ncbi.nlm.nih.gov/pubmed/24356468 http://dx.doi.org/10.1038/ncomms3976 |
Ejemplares similares
-
New Perspectives on the Role of Integrin-Linked Kinase (ILK) Signaling in Cancer Metastasis
por: McDonald, Paul C., et al.
Publicado: (2022) -
Cooperative signaling between Wnt1 and integrin-linked kinase induces accelerated breast tumor development
por: Oloumi, Arusha, et al.
Publicado: (2010) -
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization
por: Fielding, Andrew B., et al.
Publicado: (2008) -
Integrin-Linked Kinase links Dynactin-1/Dynactin-2 with cortical Integrin receptors to orient the mitotic spindle relative to the substratum
por: Morris, Edward James, et al.
Publicado: (2015) -
Integrin-Linked Kinase Regulates Interphase and Mitotic Microtubule Dynamics
por: Lim, Simin, et al.
Publicado: (2013)