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Bioinformatic analysis reveals an evolutional selection for DNA:RNA hybrid G-quadruplex structures as putative transcription regulatory elements in warm-blooded animals

Recently, we reported the co-transcriptional formation of DNA:RNA hybrid G-quadruplex (HQ) structure by the non-template DNA strand and nascent RNA transcript, which in turn modulates transcription under both in vitro and in vivo conditions. Here we present bioinformatic analysis on putative HQ-form...

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Detalles Bibliográficos
Autores principales: Xiao, Shan, Zhang, Jia-yu, Zheng, Ke-wei, Hao, Yu-hua, Tan, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905843/
https://www.ncbi.nlm.nih.gov/pubmed/23999096
http://dx.doi.org/10.1093/nar/gkt781