Optochemical control of RNA interference in mammalian cells

Short interfering RNAs (siRNAs) and microRNAs (miRNAs) have been widely used in mammalian tissue culture and model organisms to selectively silence genes of interest. One limitation of this technology is the lack of precise external control over the gene-silencing event. The use of photocleavable pr...

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Detalles Bibliográficos
Autores principales: Govan, Jeane M., Young, Douglas D., Lusic, Hrvoje, Liu, Qingyang, Lively, Mark O., Deiters, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905849/
https://www.ncbi.nlm.nih.gov/pubmed/24021631
http://dx.doi.org/10.1093/nar/gkt806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905849/
https://www.ncbi.nlm.nih.gov/pubmed/24021631
http://dx.doi.org/10.1093/nar/gkt806

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