Cargando…

Combining Hi-C data with phylogenetic correlation to predict the target genes of distal regulatory elements in human genome

Defining the target genes of distal regulatory elements (DREs), such as enhancer, repressors and insulators, is a challenging task. The recently developed Hi-C technology is designed to capture chromosome conformation structure by high-throughput sequencing, and can be potentially used to determine...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Yulan, Zhou, Yuanpeng, Tian, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905853/
https://www.ncbi.nlm.nih.gov/pubmed/24003029
http://dx.doi.org/10.1093/nar/gkt785