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Combining Hi-C data with phylogenetic correlation to predict the target genes of distal regulatory elements in human genome
Defining the target genes of distal regulatory elements (DREs), such as enhancer, repressors and insulators, is a challenging task. The recently developed Hi-C technology is designed to capture chromosome conformation structure by high-throughput sequencing, and can be potentially used to determine...
Autores principales: | Lu, Yulan, Zhou, Yuanpeng, Tian, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905853/ https://www.ncbi.nlm.nih.gov/pubmed/24003029 http://dx.doi.org/10.1093/nar/gkt785 |
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