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Mutant DnaAs of Escherichia coli that are refractory to negative control

DnaA is the initiator of DNA replication in bacteria. A mutant DnaA named DnaAcos is unusual because it is refractory to negative regulation. We developed a genetic method to isolate other mutant DnaAs that circumvent regulation to extend our understanding of mechanisms that control replication init...

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Detalles Bibliográficos
Autores principales: Chodavarapu, Sundari, Felczak, Magdalena M., Simmons, Lyle A., Murillo, Alec, Kaguni, Jon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905854/
https://www.ncbi.nlm.nih.gov/pubmed/23990329
http://dx.doi.org/10.1093/nar/gkt774