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Promoter RNA links transcriptional regulation of inflammatory pathway genes

Although many long non-coding RNAs (lncRNAs) have been discovered, their function and their association with RNAi factors in the nucleus have remained obscure. Here, we identify RNA transcripts that overlap the cyclooxygenase-2 (COX-2) promoter and contain two adjacent binding sites for an endogenou...

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Detalles Bibliográficos
Autores principales: Matsui, Masayuki, Chu, Yongjun, Zhang, Huiying, Gagnon, Keith T., Shaikh, Sarfraz, Kuchimanchi, Satya, Manoharan, Muthiah, Corey, David R., Janowski, Bethany A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905862/
https://www.ncbi.nlm.nih.gov/pubmed/23999091
http://dx.doi.org/10.1093/nar/gkt777