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Engineering modular ‘ON’ RNA switches using biological components

Riboswitches are cis-acting regulatory elements broadly distributed in bacterial mRNAs that control a wide range of critical metabolic activities. Expression is governed by two distinct domains within the mRNA leader: a sensory ‘aptamer domain’ and a regulatory ‘expression platform’. Riboswitches ha...

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Detalles Bibliográficos
Autores principales: Ceres, Pablo, Trausch, Jeremiah J., Batey, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905868/
https://www.ncbi.nlm.nih.gov/pubmed/23999097
http://dx.doi.org/10.1093/nar/gkt787