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Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes

VirB activates transcription of virulence genes in Shigella flexneri by alleviating heat-stable nucleoid-structuring protein-mediated promoter repression. VirB is unrelated to the conventional transcriptional regulators, but homologous to the plasmid partitioning proteins. We determined the crystal...

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Detalles Bibliográficos
Autores principales: Gao, Xiaopan, Zou, Tingting, Mu, Zhixia, Qin, Bo, Yang, Jian, Waltersperger, Sandro, Wang, Meitian, Cui, Sheng, Jin, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905869/
https://www.ncbi.nlm.nih.gov/pubmed/23985969
http://dx.doi.org/10.1093/nar/gkt748