Defective chromatin recruitment and retention of NHEJ core components in human tumor cells expressing a Cyclin E fragment

Exposure to genotoxic agents, such as ionizing radiation (IR), produces double-strand breaks, repaired predominantly in mammalian cells by non-homologous end-joining (NHEJ). Ku70 was identified as an interacting partner of a proteolytic Cyclin E (CycE) fragment, p18CycE. p18CycE endogenous generatio...

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Detalles Bibliográficos
Autores principales: Chatterjee, Payel, Plesca, Dragos, Mazumder, Suparna, Boutros, Jean, Yannone, Steven M., Almasan, Alexandru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905870/
https://www.ncbi.nlm.nih.gov/pubmed/24021630
http://dx.doi.org/10.1093/nar/gkt812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905870/
https://www.ncbi.nlm.nih.gov/pubmed/24021630
http://dx.doi.org/10.1093/nar/gkt812

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