In-cell optical imaging of exogenous G-quadruplex DNA by fluorogenic ligands

Guanine-rich oligonucleotides (GROs) are promising therapeutic candidate for cancer treatment and other biomedical application. We have introduced a G-quadruplex (G4) ligand, 3,6-bis(1-methyl-4-vinylpyridinium) carbazole diiodide, to monitor the cellular uptake of naked GROs and map their intracellu...

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Detalles Bibliográficos
Autores principales: Tseng, Ting-Yuan, Wang, Zi-Fu, Chien, Cheng-Hao, Chang, Ta-Chau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905880/
https://www.ncbi.nlm.nih.gov/pubmed/24030712
http://dx.doi.org/10.1093/nar/gkt814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905880/
https://www.ncbi.nlm.nih.gov/pubmed/24030712
http://dx.doi.org/10.1093/nar/gkt814

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