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Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation
Translesion DNA synthesis (TLS) can use specialized DNA polymerases to insert and/or extend nucleotides across lesions, thereby limiting stalled replication fork collapse and the potential for cell death. Recent studies have shown that monoubiquitinated proliferating cell nuclear antigen (PCNA) play...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905884/ https://www.ncbi.nlm.nih.gov/pubmed/24038355 http://dx.doi.org/10.1093/nar/gkt793 |