A transient α-helical molecular recognition element in the disordered N-terminus of the Sgs1 helicase is critical for chromosome stability and binding of Top3/Rmi1

The RecQ-like DNA helicase family is essential for the maintenance of genome stability in all organisms. Sgs1, a member of this family in Saccharomyces cerevisiae, regulates early and late steps of double-strand break repair by homologous recombination. Using nuclear magnetic resonance spectroscopy,...

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Detalles Bibliográficos
Autores principales: Kennedy, Jessica A., Daughdrill, Gary W., Schmidt, Kristina H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905885/
https://www.ncbi.nlm.nih.gov/pubmed/24038467
http://dx.doi.org/10.1093/nar/gkt817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905885/
https://www.ncbi.nlm.nih.gov/pubmed/24038467
http://dx.doi.org/10.1093/nar/gkt817

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