The mycobacterial antibiotic resistance determinant WhiB7 acts as a transcriptional activator by binding the primary sigma factor SigA (RpoV)

Tuberculosis therapeutic options are limited by the high intrinsic antibiotic resistance of Mycobacterium tuberculosis. The putative transcriptional regulator WhiB7 is crucial for the activation of systems that provide resistance to diverse antibiotic classes. Here, we used in vitro run-off, two-hyb...

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Detalles Bibliográficos
Autores principales: Burian, Ján, Yim, Grace, Hsing, Michael, Axerio-Cilies, Peter, Cherkasov, Artem, Spiegelman, George B., Thompson, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905903/
https://www.ncbi.nlm.nih.gov/pubmed/23990327
http://dx.doi.org/10.1093/nar/gkt751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905903/
https://www.ncbi.nlm.nih.gov/pubmed/23990327
http://dx.doi.org/10.1093/nar/gkt751

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