From Ugly Duckling to Swan: Unexpected Identification from Cell-SELEX of an Anti-Annexin A2 Aptamer Targeting Tumors

BACKGROUND: Cell-SELEX is now widely used for the selection of aptamers against cell surface biomarkers. However, despite negative selection steps using mock cells, this method sometimes results in aptamers against undesirable targets that are expressed both on mock and targeted cells. Studying thes...

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Detalles Bibliográficos
Autores principales: Cibiel, Agnes, Nguyen Quang, Nam, Gombert, Karine, Thézé, Benoit, Garofalakis, Anikitos, Ducongé, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906106/
https://www.ncbi.nlm.nih.gov/pubmed/24489826
http://dx.doi.org/10.1371/journal.pone.0087002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906106/
https://www.ncbi.nlm.nih.gov/pubmed/24489826
http://dx.doi.org/10.1371/journal.pone.0087002

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