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Urine MicroRNA as Potential Biomarkers of Autosomal Dominant Polycystic Kidney Disease Progression: Description of miRNA Profiles at Baseline

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is clinically heterogenic. Biomarkers are needed to predict prognosis and guide management. We aimed to profile microRNA (miRNA) in ADPKD to gain molecular insight and evaluate biomarker potential. METHODS: Small-RNA libraries were gen...

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Detalles Bibliográficos
Autores principales: Ben-Dov, Iddo Z., Tan, Ying-Cai, Morozov, Pavel, Wilson, Patricia D., Rennert, Hanna, Blumenfeld, Jon D., Tuschl, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906110/
https://www.ncbi.nlm.nih.gov/pubmed/24489795
http://dx.doi.org/10.1371/journal.pone.0086856