ICAM-1-Based Rabies Virus Vaccine Shows Increased Infection and Activation of Primary Murine B Cells In Vitro and Enhanced Antibody Titers In-Vivo

We have previously shown that live-attenuated rabies virus (RABV)-based vaccines infect and directly activate murine and human primary B cells in-vitro, which we propose can be exploited to help develop a single-dose RABV-based vaccine. Here we report on a novel approach to utilize the binding of In...

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Detalles Bibliográficos
Autores principales: Norton, James E., Lytle, Andrew G., Shen, Shixue, Tzvetkov, Evgeni P., Dorfmeier, Corin L., McGettigan, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906113/
https://www.ncbi.nlm.nih.gov/pubmed/24489846
http://dx.doi.org/10.1371/journal.pone.0087098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906113/
https://www.ncbi.nlm.nih.gov/pubmed/24489846
http://dx.doi.org/10.1371/journal.pone.0087098

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