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A Low Gastric pH Mouse Model to Evaluate Live Attenuated Bacterial Vaccines
The low pH of the stomach serves as a barrier to ingested microbes and must be overcome or bypassed when delivering live bacteria for vaccine or probiotic applications. Typically, the impact of stomach acidity on bacterial survival is evaluated in vitro, as there are no small animal models to evalua...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906194/ https://www.ncbi.nlm.nih.gov/pubmed/24489912 http://dx.doi.org/10.1371/journal.pone.0087411 |