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A Low Gastric pH Mouse Model to Evaluate Live Attenuated Bacterial Vaccines

The low pH of the stomach serves as a barrier to ingested microbes and must be overcome or bypassed when delivering live bacteria for vaccine or probiotic applications. Typically, the impact of stomach acidity on bacterial survival is evaluated in vitro, as there are no small animal models to evalua...

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Detalles Bibliográficos
Autores principales:	Brenneman, Karen E., Willingham, Crystal, Kilbourne, Jacquelyn A., 3rd, Roy Curtiss, Roland, Kenneth L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906194/ https://www.ncbi.nlm.nih.gov/pubmed/24489912 http://dx.doi.org/10.1371/journal.pone.0087411

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