Simvastatin Impairs Growth Hormone-Activated Signal Transducer and Activator of Transcription (STAT) Signaling Pathway in UMR-106 Osteosarcoma Cells

Recent studies have demonstrated that statins reduce cell viability and induce apoptosis in various types of cancer cells. The molecular mechanisms underlying these effects are poorly understood. The JAK/STAT pathway plays an important role in the regulation of proliferation and apoptosis in many ti...

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Detalles Bibliográficos
Autores principales: Sandoval-Usme, María Claudia, Umaña-Pérez, Adriana, Guerra, Borja, Hernández-Perera, Orlando, García-Castellano, José Manuel, Fernández-Pérez, Leandro, Sánchez-Gómez, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906206/
https://www.ncbi.nlm.nih.gov/pubmed/24489959
http://dx.doi.org/10.1371/journal.pone.0087769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906206/
https://www.ncbi.nlm.nih.gov/pubmed/24489959
http://dx.doi.org/10.1371/journal.pone.0087769

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