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C26 Cancer-Induced Muscle Wasting Is IKKβ-Dependent and NF-kappaB-Independent

Existing data suggest that NF-kappaB signaling is a key regulator of cancer-induced skeletal muscle wasting. However, identification of the components of this signaling pathway and of the NF-κB transcription factors that regulate wasting is far from complete. In muscles of C26 tumor bearing mice, ov...

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Detalles Bibliográficos
Autores principales: Cornwell, Evangeline W., Mirbod, Azadeh, Wu, Chia-Ling, Kandarian, Susan C., Jackman, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906224/
https://www.ncbi.nlm.nih.gov/pubmed/24489962
http://dx.doi.org/10.1371/journal.pone.0087776