Targeted Methylation of the Epithelial Cell Adhesion Molecule (EpCAM) Promoter to Silence Its Expression in Ovarian Cancer Cells

The Epithelial Cell Adhesion Molecule (EpCAM) is overexpressed in many cancers including ovarian cancer and EpCAM overexpression correlates with decreased survival of patients. It was the aim of this study to achieve a targeted methylation of the EpCAM promoter and silence EpCAM gene expression usin...

Descripción completa

Detalles Bibliográficos
Autores principales: Nunna, Suneetha, Reinhardt, Richard, Ragozin, Sergey, Jeltsch, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906225/
https://www.ncbi.nlm.nih.gov/pubmed/24489952
http://dx.doi.org/10.1371/journal.pone.0087703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906225/
https://www.ncbi.nlm.nih.gov/pubmed/24489952
http://dx.doi.org/10.1371/journal.pone.0087703

Ejemplares similares