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Targeted Methylation of the Epithelial Cell Adhesion Molecule (EpCAM) Promoter to Silence Its Expression in Ovarian Cancer Cells
The Epithelial Cell Adhesion Molecule (EpCAM) is overexpressed in many cancers including ovarian cancer and EpCAM overexpression correlates with decreased survival of patients. It was the aim of this study to achieve a targeted methylation of the EpCAM promoter and silence EpCAM gene expression usin...
Autores principales: | Nunna, Suneetha, Reinhardt, Richard, Ragozin, Sergey, Jeltsch, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906225/ https://www.ncbi.nlm.nih.gov/pubmed/24489952 http://dx.doi.org/10.1371/journal.pone.0087703 |
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