Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets

We have previously shown that peculiar metabolic features of cell adaptation and survival in hypoxia imply growth restriction points that are typical of embryonic stem cells and disappear with differentiation. Here we provide evidence that such restrictions can be exploited as specific antiblastic t...

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Detalles Bibliográficos
Autores principales: Cipolleschi, Maria Grazia, Marzi, Ilaria, Santini, Roberta, Fredducci, David, Vinci, Maria Cristina, D’Amico, Massimo, Rovida, Elisabetta, Stivarou, Theodora, Torre, Eugenio, Dello Sbarba, Persio, Stecca, Barbara, Olivotto, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906243/
https://www.ncbi.nlm.nih.gov/pubmed/24200964
http://dx.doi.org/10.4161/cc.27031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906243/
https://www.ncbi.nlm.nih.gov/pubmed/24200964
http://dx.doi.org/10.4161/cc.27031

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