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Inhibition of c-Kit signaling by diosmetin isolated from Chrysanthemum morifolium

The interaction of stem cell factor (SCF) with its cognate receptor c-Kit is closely associated with the survival and maturation of melanocytes. To investigate novel depigmentation agents, we screened 2,000 plant extracts for c-Kit inhibitors to identify active small molecules by using time-resolved...

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Detalles Bibliográficos
Autores principales: Lee, Seong Jin, Jung, Tae-Hoon, Kim, Hojeong, Jeong, Daeyoung, Choi, Gildon, Park, Woo-Kyu, Kong, Jae Yang, Jin, Mu-Hyun, Cho, Heeyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906526/
https://www.ncbi.nlm.nih.gov/pubmed/23709168
http://dx.doi.org/10.1007/s12272-013-0158-7