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Inhibition of c-Kit signaling by diosmetin isolated from Chrysanthemum morifolium
The interaction of stem cell factor (SCF) with its cognate receptor c-Kit is closely associated with the survival and maturation of melanocytes. To investigate novel depigmentation agents, we screened 2,000 plant extracts for c-Kit inhibitors to identify active small molecules by using time-resolved...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906526/ https://www.ncbi.nlm.nih.gov/pubmed/23709168 http://dx.doi.org/10.1007/s12272-013-0158-7 |