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Microbials for the production of monoclonal antibodies and antibody fragments

Monoclonal antibodies (mAbs) and antibody fragments represent the most important biopharmaceutical products today. Because full length antibodies are glycosylated, mammalian cells, which allow human-like N-glycosylation, are currently used for their production. However, mammalian cells have several...

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Detalles Bibliográficos
Autores principales: Spadiut, Oliver, Capone, Simona, Krainer, Florian, Glieder, Anton, Herwig, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906537/
https://www.ncbi.nlm.nih.gov/pubmed/24183828
http://dx.doi.org/10.1016/j.tibtech.2013.10.002