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Expanding the substrate scope of ugi five-center, four-component reaction U-5C-4CR): ketones as coupling partners for secondary amino acids

Various symmetrical and unsymmetrical ketones were successfully coupled with secondary amino acids in the course of Ugi five-center, four-component reaction (U-5C-4CR), thus expanding the molecular diversity possible to be achieved by the reaction. The chemical yields depended on the degree of hindr...

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Detalles Bibliográficos
Autores principales: Dawidowski, Maciej, Sobczak, Sławomir, Wilczek, Marcin, Kulesza, Artur, Turło, Jadwiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906574/
https://www.ncbi.nlm.nih.gov/pubmed/24154732
http://dx.doi.org/10.1007/s11030-013-9488-0