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Loss of pigment epithelium-derived factor: a novel mechanism for the development of endocrine resistance in breast cancer
INTRODUCTION: Despite the benefits of endocrine therapies such as tamoxifen and aromatase inhibitors in treating estrogen receptor (ER) alpha-positive breast cancer, many tumors eventually become resistant. The molecular mechanisms governing resistance remain largely unknown. Pigment epithelium-deri...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906603/ https://www.ncbi.nlm.nih.gov/pubmed/23151593 http://dx.doi.org/10.1186/bcr3356 |