Loss of pigment epithelium-derived factor: a novel mechanism for the development of endocrine resistance in breast cancer

INTRODUCTION: Despite the benefits of endocrine therapies such as tamoxifen and aromatase inhibitors in treating estrogen receptor (ER) alpha-positive breast cancer, many tumors eventually become resistant. The molecular mechanisms governing resistance remain largely unknown. Pigment epithelium-deri...

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Detalles Bibliográficos
Autores principales: Jan, Rifat, Huang, Min, Lewis-Wambi, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906603/
https://www.ncbi.nlm.nih.gov/pubmed/23151593
http://dx.doi.org/10.1186/bcr3356

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