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Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2
Myostatin, a negative regulator of skeletal muscle growth, is produced from myostatin precursor by multiple steps of proteolytic processing. After cleavage by a furin-type protease, the propeptide and growth factor domains remain associated, forming a noncovalent complex, the latent myostatin comple...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906830/ https://www.ncbi.nlm.nih.gov/pubmed/23829672 http://dx.doi.org/10.1111/febs.12377 |