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Mutations of the domain forming the dimeric interface of the ArdA protein affect dimerization and antimodification activity but not antirestriction activity

ArdA antirestriction proteins are encoded by genes present in many conjugative plasmids and transposons within bacterial genomes. Antirestriction is the ability to prevent cleavage of foreign incoming DNA by restriction-modification (RM) systems. Antimodification, the ability to inhibit modification...

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Detalles Bibliográficos
Autores principales: Roberts, Gareth A, Chen, Kai, Bower, Edward K M, Madrzak, Julia, Woods, Arcadia, Barker, Amy M, Cooper, Laurie P, White, John H, Blakely, Garry W, Manfield, Iain, Dryden, David T F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906837/
https://www.ncbi.nlm.nih.gov/pubmed/23910724
http://dx.doi.org/10.1111/febs.12467