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Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes

Aims Sodium–glucose co-transporter 2 (SGLT2) reabsorbs glucose and sodium in the renal proximal tubule. Dapagliflozin, an SGLT2 inhibitor, targets hyperglycaemia in type 2 diabetes by increasing renal glucose excretion. To investigate whether the parallel occurring sodium loss would have diuretic-li...

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Detalles Bibliográficos
Autores principales: Heerspink, H J Lambers, de Zeeuw, D, Wie, L, Leslie, B, List, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906841/
https://www.ncbi.nlm.nih.gov/pubmed/23668478
http://dx.doi.org/10.1111/dom.12127