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NMR Localization of Divalent Cations at the Active Site of the Neurospora VS Ribozyme Provides Insights into RNA–Metal-Ion Interactions

[Image: see text] Metal cations represent key elements of RNA structure and function. In the Neurospora VS ribozyme, metal cations play diverse roles; they are important for substrate recognition, formation of the active site, and shifting the pK(a)’s of two key nucleobases that contribute to the ge...

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Detalles Bibliográficos
Autores principales: Bonneau, Eric, Legault, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906864/
https://www.ncbi.nlm.nih.gov/pubmed/24364590
http://dx.doi.org/10.1021/bi401484a