A yeast phenomic model for the gene interaction network modulating CFTR-ΔF508 protein biogenesis

BACKGROUND: The overall influence of gene interaction in human disease is unknown. In cystic fibrosis (CF) a single allele of the cystic fibrosis transmembrane conductance regulator (CFTR-ΔF508) accounts for most of the disease. In cell models, CFTR-ΔF508 exhibits defective protein biogenesis and de...

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Detalles Bibliográficos
Autores principales: Louie, Raymond J, Guo, Jingyu, Rodgers, John W, White, Rick, Shah, Najaf A, Pagant, Silvere, Kim, Peter, Livstone, Michael, Dolinski, Kara, McKinney, Brett A, Hong, Jeong, Sorscher, Eric J, Bryan, Jennifer, Miller, Elizabeth A, Hartman, John L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906889/
https://www.ncbi.nlm.nih.gov/pubmed/23270647
http://dx.doi.org/10.1186/gm404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906889/
https://www.ncbi.nlm.nih.gov/pubmed/23270647
http://dx.doi.org/10.1186/gm404

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