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Prostaglandin F(2α) FP receptor antagonist improves outcomes after experimental traumatic brain injury

BACKGROUND: Injuries to the brain promote upregulation of prostaglandins, notably the proinflammatory PGF(2α), and overactivation of their cognate G-protein-coupled FP receptor, which could exacerbate neuronal damage. Our study is focused on investigation of the FP receptor as a target for novel neu...

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Detalles Bibliográficos
Autores principales: Glushakov, Alexander V, Robbins, Sean W, Bracy, Connor L, Narumiya, Shuh, Doré, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907016/
https://www.ncbi.nlm.nih.gov/pubmed/24172576
http://dx.doi.org/10.1186/1742-2094-10-132