Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer’s disease

BACKGROUND: Alzheimer’s disease affects more than 35 million people worldwide but there is no known cure. Age is the strongest risk factor for Alzheimer’s disease but it is not clear how age-related changes impact the disease. Here, we used a mouse model of Alzheimer’s disease to identify age-specif...

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Detalles Bibliográficos
Autores principales: Jackson, Harriet M, Soto, Ileana, Graham, Leah C, Carter, Gregory W, Howell, Gareth R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907022/
https://www.ncbi.nlm.nih.gov/pubmed/24274089
http://dx.doi.org/10.1186/1471-2164-14-831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907022/
https://www.ncbi.nlm.nih.gov/pubmed/24274089
http://dx.doi.org/10.1186/1471-2164-14-831

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